Case Studies - Process Design
Setting Objectives to Commercialise an Innovation Project
Facing the challenge of needing to know whether to commit further to the commercialisation of an innovative process in the early stages when data is limited, the partners in the LevWave collaboration were able to benefit from Britest successfully piloting an understanding-based methodology for setting commercialisation objectives allowing key risks and knowledge gaps to be identified and addressed.
KUDOS - Sharing collective process insight
Right across the process industries manufacturers use similar unit operations and face similar challenges as they strive to optimise their performance. At the same time, collaborative research projects often struggle to disseminate fresh insights about process technologies widely and in ways that endure. Britest Knowledge and Understanding Domains (KUDOS) collate process understanding, generated through projects, in a form that allows process sector companies to learn about different process operations and challenges.
Increasing Production of a Speciality Chemical by 50% to meet demand
This case study describes how a Britest study enabled an internal cross-functional team at Robinson Brothers Limited to rapidly identify and implement process changes designed to improve efficiency and up time, making it possible to support extra sales of ~£1M p.a.
A Structured Approach to Whole Process Review
Read how Britest has enabled biotechnology pioneers Biogen to conduct a structured review of manufacturing operations with an end-to-end view of the entire manufacturing process in order to guarantee product quality and robustness.
Supporting Complex Decision Making in Route Selection
For complex, multiple step separations there are often many possible routes to the end product. This is exacerbated if several products are to be manufactured from a single feed-stream. Faced with this challenge, Johnson Matthey turned to Britest tools and methodologies to find the optimal process route for separation of platinum group metals.
Process Options - Balancing Development Risk and Commercial Opportunity
In process development several potentially viable options may be on the table, each with its own complicated risk - reward relationship. This case study from Johnson Matthey shows how a process development team used Britest to make progress in deciding between several process options with disparate project/developmental risks and potential commercial impact.without sacrificing appropriate rigour in their decision making process.
Gap Analysis at the Start of New Process Development
Britest facilitation of a process for open dialogue between manufacturers, equipment providers and key stakeholders provided the framework for dialogue needed for Johnson Matthey to engage in a collaborative research and development programme to develop an improvement approach to recycling Platinum Group Metals. Beneficial outcomes were minimisation of research risk, identification of uncertainty, and stakeholder buy-in.
Supporting scale-up in an innovative start-up business
Conductive Organics, is a University of Strathclyde spin-out company, working to produce the next generation of conductive organic materials for use in emerging technologies such as Organic Light Emitting Diodes (OLED's). A Britest study enabled Conductive Organics to address the challenge of scaling-up the synthesis of the key organic compound at the heart of their innovative formulations, and to gather underpinning information to support their emerging business plan.
Rapid optimisation of a new process in Pharmaceutical API manufacture
Read how Britest successfully provided the structured approach needed by a process development centre within a large multi-national pharmaceutical business to optimise a new process in a very short time period.
Collaboration, customer focus and value creation - delivering JM's core values
Johnson Matthey Emission Control Technologies develops and manufactures coated catalyst systems for automotive applications. This case study exemplifies a typical study where Britest tools act as a focus to bring together different disciplines and business locations in collaborative programmes allowing JM to deliver its core values.
Britest Improvement Study to Increase Throughput by 50%
This case study describes the elements of a Britest throughput improvement study carried out by a custom synthesis manufacturer to meet an identified customer need to increase process throughput by at least 50% within three years, which was successfully delivered by halving batch times.
Technology Transfer Made Easy in a Contract Manufacturing Organisation
Read how a Britest facilitator was able to help a contract manufacturing organisation who did not know the Britest tools identify a common language for effective technology transfer.
Challenging ideas on an established manufacturing process
How do you reduce costs and drive value when you've been operating a process for 25 years? This Britest study with a fine chemical company did exactly that by challenging established idea of what was and wasn't optimal in the process chemistry to speed up and simplify the reaction route.